Scientists Develop New Ways to Assemble Genomes Faster and More Accurately
In a bid to figure out how genomes can be assembled faster and more accurately, scientists have developed a new method for piecing together the short DNA reads produced by next-generation sequencing technologies. These are responsible for building complete genome sequences.
Scientists at the University of Massachusetts Medical School have proved that entire genomes can be assembled faster and accurately by using measurements and using 3D shape. Yes, measuring frequency of interactions between DNA segments and 3D shapes as a guide makes it possible.
This technique really helped the scientists place 65 previously unaccounted for DNA fragments in incomplete regions of the human genome.
Dr. Dekker is co-director of the Program in Systems Biology, professor of biochemistry and molecular pharmacology at UMMS and senior author of the study. He said, "The ability of next-generation sequencing technologies to produce hundreds of millions of short reads of DNA sequences has been an incredible boon for biomedical researchers".
He said the 3D structure of the genome as a guide has made it possible to quickly, cheaply and more accurately assemble these snippets of DNA than current methodologies.
This new study has opened doors for scientists to complete the human genome. Besides, it allows assembling the genomes of any other species and facilitating new genetic discoveries more quickly.
It has become an effort in futility to cast blame...Read More
The newly elected leader of the Republican Party in...Read More
On Monday this week, the French government accepted...Read More
French Prime Minister Edouard Philippe is being...Read More
A new television channel in France, RT France, Took...Read More