Gene Mutation Causes Variations for East Asians

Gene Mutation Causes Variations for East Asians

An insight by the researchers to understand the manner in which the East Asians must have evolved has opened up a new avenue for gene study.

Features like thicker hair shafts, more sweat glands, typically identified teeth and smaller breasts have been attributed to gene mutations that had occurred 35,000 years ago.

The discovery is specific but can also be used in 400 different sites of human genome. Researchers have stated that DNA variations at this site can be held responsible for the human evolution, especially East Asian people.

Researchers delved into the characteristics of gene known as EDAR. The cause of difference was noticed as one of the gene units was found to be mutated for the East Asians and other races carry the standard gene.

To confirm the inference, team of researchers led by Yana G. Kamberov and Pardis C. Sabeti at the Broad Institute in Cambridge, Mass., tested the gene in mice.

Mice already possess EDAR. The team brought a change in the DNA structure of the gene. Results were positive as the mice grew older; it was getting covered with thick hair.

The finding of the experiment has to take a proper shape as Joshua Akey, a geneticist at the University of Washington in Seattle, said, "A reflection of good science is that a step forward opens up a lot more questions".


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