Protein in Breast Milk May Reverse Antibiotic Resistance

Protein in Breast Milk May Reverse Antibiotic Resistance

Published in PLoS ONE, a research finding has asserted that a protein in breast milk can help in reversing the antibiotic resistance. This will give a new ray of hope to fight the diseases like pneumonia and staph infections.

The research was conducted by the University of Buffalo. It was based on lab experiments using petri dishes and animals to test the protein complex called Human Alpha-lactalbumin Made Lethal to Tumor Cells (HAMLET).

It was found that the compound was able to increase the sensitivity of tough bacteria to antibiotics. Subsequently, it reverses the resistance and allows a lower antibiotic dose while sick mice were treated. Experiments show that penicillin-resistant Streptococcus pneumoniae and methicillin-resistant Staphylococcus aureus, regained the sensitivity to the antibiotics.

Anders Hakansson, the Lead Researcher and a UB Assistant Professor of microbiology and immunology, said, "HAMLET has the potential to minimize the concentrations of antibiotics we need to use to fight infections, and enable us to use well-established antibiotics against resistant strains again".

The researchers said that the protein complex can be used in human beings together with the existing antibiotics. This helps to combat the drug resistant bacteria and superbugs. The study was authored by Laura Marks, Anders Hakansson and UB Ph. D. student Emily Clementi.


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