Aspirin Response Determined by Genes Marker IDs

Aspirin Response Determined by Genes Marker IDs

A recent research has said that a gene marker IDs has been developed for finding response to aspirin treatment. It is defined as a group of 60 genes that predict about death or myocardial infarction. This can predict the situation after cardiac catheterization. The facts have been included in the online Journal of the American College of Cardiology.

These 60 co-expressed genes are called the Aspirin Response Signature (ARS). According to one of the researchers, these genes are important for platelet function. They are divided into two groups of healthy volunteers. One of them includes 325 mg of aspirin per day; other one included a group of cardiology patients that take 81 mg of aspirin per day.

Deepak Voora, MD, of Duke University has said, "Physicians could potentially use as a diagnostic test to identify those who are adequately responding to aspirin or not, and also to identify those individuals who are at highest risk for MI and death in patients who are taking aspirin". This whole blood-based biomarker has been developed by the researchers.

The researchers have explained the fact that the research was restricted because of the dearth of platelet function. There was a lack of platelet volume measurements in the CATHGEN cohorts, according to the authors of the study.


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