Scientists identify protein that plays central role on heart beats
A team of scientists has said that it has identified a protein that plays a central role incontinuous heartbeat and they belie that the discovery can help develop new cures for heart problems.
Experts have said that heart beats should be precisely calibrated as even a small divergence from the metronomic rhythm may cause problems and even death. The team discovered for the first time how myosin-binding protein C enables muscle fibers in the heart to work in perfect synchrony.
W. Jonathan Lederer, professor of physiology at the University of Maryland School of Medicine said that the team found that the protein is important for the process. It was known that calcium acts as a trigger for the heartbeat as it activates proteins that cause the sarcomeresto contract. These sarcomeres are fibrous proteins that make up heart muscle cells. Experts have said that average heart beats 35 million times a year and 2.5 billion times over a lifetime.
Dr. Lederer said, "This protein turns out to be really important to this process. This is a really exciting finding. We envision a lot of research that we can do with this new knowledge. We will continue to investigate this in all kinds of ways."
Dean E. Albert Reece, MD, PhD, MBA, who is also the vice president for Medical Affairs, University of Maryland, and the John Z. and Akiko K. Bowers Distinguished Professor and Dean of the School of Medicine said that the new research is a great example of collaborative basic science research that may have huge implicaitons.
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